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Table 2 Clinical manifestations, laboratory data, and outcome of 88 meningococcal disease patients with completed case records: serogroup W135 versus non-W135.

From: Clinical features and outcome of sporadic serogroup W135 disease Taiwan

Feature W135 (n = 21) Non-W135 (n = 67) Total (n = 88) P
No underlying disease 16(76.2) 53(79.1) 69(78.4) 0.768
Underlying disease of cancer 2(9.5) 4(6.0) 6(6.8) 0.626
Steroid use 2(9.5) 2(3.0) 4(4.5) 0.240
Disease classification     
   Meningitis 10(47.6) 40(59.7) 50(56.8) 0.329
   Bacteremia without meningitis 11(52.4) 27(40.3) 38(43.2) 0.329
Bacteremia without sepsis 2(9.5) 5(7.5) 7(8.0) 0.670
With pneumonia 5(23.8) 1(1.5) 6(6.8) 0.003
With arthritis 1(4.8) 2(3.0) 3(3.4) 0.563
Presentation     
   Presentation ≤1 day after symptom onset 12 (57.1) 45 (67.2) 57 (64.8) 0.402
   Presentation days (mean ± SD) 1.9 ± 2.4 1.7 ± 3.0 1.8 ± 2.9 0.810
   Fever 17(81.0) 58(86.6) 75(85.2) 0.501
   Sore throat 6(28.6) 16(23.9) 22(25.0) 0.665
   Cough 12(57.1) 29(43.3) 41(46.6) 0.267
   Myalgia and/or arthragia 5(23.8) 18(26.9) 23(26.1) 0.781
   Nausea and/or vomiting 8(38.1) 35(52.2) 43(48.9) 0.258
   Headache 7(33.3) 26(38.8) 33(37.5) 0.651
   Petechia and/or purpura 6(28.6) 26(38.8) 32(36.4) 0.395
   Altered mental status 8(38.1) 31(46.3) 39(44.3) 0.511
   Seizures 2(9.5) 5(7.5) 7(8.0) 0.670
Laboratory data     
   WBC count < 10,000/mm3 10(47.6) 26(38.8) 36(40.9) 0.474
   Platelet < 100,000/mm3 6(28.6) 22(32.8) 28(31.8) 0.714
Cerebrospinal fluida     
   WBC count >1000/mm3 3/10(30.0) 29/40(72.5) 32/50(64.0) 0.024
   WBC count 100–1000/mm3 5/10(50.0) 8/40(20.0) 13/50(26.0) 0.101
   WBC count <100/mm3 2/10(20.0) 3/40(7.5) 5/50(10.0) 0.258
   Protein > 300 mg/dl 4/9(44.4) 11/36(30.6) 15/45(33.3) 0.454
   Glucose < 10 mg/dl 5/9(55.6) 18/35(51.4) 23/44(52.3) 1.000
Days from presentation to antibiotics use (mean ± SD) 0.7 ± 1.0 2.2 ± 5.0 1.8 ± 4.4 0.200
Outcome     
   Shock 11(52.4) 21(31.3) 32 (36.4) 0.080
   Intubation 9 (42.9) 16(23.9) 25(28.4) 0.092
   Attributable death 4(19.0) 15(22.4) 19(21.6) 1.000
   Death within 48 hours 2(9.5) 13(19.4) 15(17.0) 0.293
  1. NOTE. Data are no. (%) of patients, unless otherwise indicated. WBC: white blood cells.
  2. a Cerebrospinal fluid data were analyzed in meningitis patients only.