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Table 2 Clinical manifestations, laboratory data, and outcome of 88 meningococcal disease patients with completed case records: serogroup W135 versus non-W135.

From: Clinical features and outcome of sporadic serogroup W135 disease Taiwan

Feature

W135 (n = 21)

Non-W135 (n = 67)

Total (n = 88)

P

No underlying disease

16(76.2)

53(79.1)

69(78.4)

0.768

Underlying disease of cancer

2(9.5)

4(6.0)

6(6.8)

0.626

Steroid use

2(9.5)

2(3.0)

4(4.5)

0.240

Disease classification

    

   Meningitis

10(47.6)

40(59.7)

50(56.8)

0.329

   Bacteremia without meningitis

11(52.4)

27(40.3)

38(43.2)

0.329

Bacteremia without sepsis

2(9.5)

5(7.5)

7(8.0)

0.670

With pneumonia

5(23.8)

1(1.5)

6(6.8)

0.003

With arthritis

1(4.8)

2(3.0)

3(3.4)

0.563

Presentation

    

   Presentation ≤1 day after symptom onset

12 (57.1)

45 (67.2)

57 (64.8)

0.402

   Presentation days (mean ± SD)

1.9 ± 2.4

1.7 ± 3.0

1.8 ± 2.9

0.810

   Fever

17(81.0)

58(86.6)

75(85.2)

0.501

   Sore throat

6(28.6)

16(23.9)

22(25.0)

0.665

   Cough

12(57.1)

29(43.3)

41(46.6)

0.267

   Myalgia and/or arthragia

5(23.8)

18(26.9)

23(26.1)

0.781

   Nausea and/or vomiting

8(38.1)

35(52.2)

43(48.9)

0.258

   Headache

7(33.3)

26(38.8)

33(37.5)

0.651

   Petechia and/or purpura

6(28.6)

26(38.8)

32(36.4)

0.395

   Altered mental status

8(38.1)

31(46.3)

39(44.3)

0.511

   Seizures

2(9.5)

5(7.5)

7(8.0)

0.670

Laboratory data

    

   WBC count < 10,000/mm3

10(47.6)

26(38.8)

36(40.9)

0.474

   Platelet < 100,000/mm3

6(28.6)

22(32.8)

28(31.8)

0.714

Cerebrospinal fluida

    

   WBC count >1000/mm3

3/10(30.0)

29/40(72.5)

32/50(64.0)

0.024

   WBC count 100–1000/mm3

5/10(50.0)

8/40(20.0)

13/50(26.0)

0.101

   WBC count <100/mm3

2/10(20.0)

3/40(7.5)

5/50(10.0)

0.258

   Protein > 300 mg/dl

4/9(44.4)

11/36(30.6)

15/45(33.3)

0.454

   Glucose < 10 mg/dl

5/9(55.6)

18/35(51.4)

23/44(52.3)

1.000

Days from presentation to antibiotics use (mean ± SD)

0.7 ± 1.0

2.2 ± 5.0

1.8 ± 4.4

0.200

Outcome

    

   Shock

11(52.4)

21(31.3)

32 (36.4)

0.080

   Intubation

9 (42.9)

16(23.9)

25(28.4)

0.092

   Attributable death

4(19.0)

15(22.4)

19(21.6)

1.000

   Death within 48 hours

2(9.5)

13(19.4)

15(17.0)

0.293

  1. NOTE. Data are no. (%) of patients, unless otherwise indicated. WBC: white blood cells.
  2. a Cerebrospinal fluid data were analyzed in meningitis patients only.