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Table 1 Geographic distribution, age, and viral isolates from 802 children with aseptic meningitis

From: Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study of aseptic meningitis

Institution

No. cases year 1

No. cases year 2

Median age of children

year 1 (range)

Median age of children

year 2 (range)

Viral isolates

in year 1

Viral isolates

in year 2

Vancouver, British Columbia†

16

10

7.6 (0.03 – 16.5)

5.6 (0.20 – 15.6)

Coxsackie A09 (N = 1), Enterovirus unspecified type (N = 4)

Enterovirus unspecified type (N = 1)

Calgary, Alberta

179

27

8.2 (0.00 – 18.0)

5.4 (0.10 – 18.0)

Echovirus unspecified type (N = 1), Echovirus 09 (N = 2), Echovirus 30 (N = 25), Enterovirus unspecified type (N = 6), Enterovirus 02 (N = 1), Enterovirus 30 (N = 1), Enterovirus identified by PCR unspecified typed (N = 5)

Echovirus 30 (N = 1)

Edmonton, Alberta

174

37

9.5 (0.01 – 18.0)

7.2 (0.00 – 18.5)

Coxsackie B (N = 1), Echovirus unspecified typed (N = 3), Enterovirus unspecified type (N = 2), Enterovirus identified by PCR unspecified typed (N = 22)

Enterovirus unspecified type (N = 1), Enterovirus identified by PCR unspecified typed (N = 1)

Saskatoon, Saskatchewan

37

5

8 (0.05 – 18.0)

4.1 (0.5 – 16.3)

Echovirus unspecified type (N = 5)

N = 0

Winnipeg, Manitoba

92

21

7.2 (0.02 – 15.9)

4.6 (0.02 – 11.8)

Coxsackie B (N = 1), Echovirus 02 (N = 1), Echovirus 11 (N = 9), Echovirus 30 (N = 35), Enterovirus unspecified type (N = 4), Enterovirus identified by PCR unspecified typed (N = 14)

Coxsackie A09 (N = 5), Enterovirus unspecified type (N = 3)

Toronto, Ontario†

42

40

0.7 (0.02 – 17.2)

1.5 (0.01 – 16.0)

Enterovirus unspecified type (N = 4)*, Enterovirus identified by PCR unspecified typed (N = 10)

Enterovirus unspecified type (N = 6), Enterovirus identified by PCR unspecified typed (N = 7)

Montreal, Quebec

53

50

1.2 (0.03 – 15.2)

6.4 (0.01 – 15.4)

Coxsackie A09 (N = 1), Coxsackie B2 (N = 3), Coxsackie B3 (N = 1), Echovirus 09 (N = 7), Echovirus 11 (N = 1), Echovirus 30 (N = 4), Enterovirus 70/71 (N = 3), Enterovirus 02 (N = 1)

Coxsackie B2 (N = 2), Coxsackie B5 (N = 1), Echovirus 06 (N = 6), Echovirus 09 (N = 2), Echovirus 11 (N = 6), Echovirus 30 (N = 5), Enterovirus unspecified typed (N = 1)

Halifax, Nova Scotia†

10

9

4.3 (0.00 – 15.2)

0.7 (0.02 – 15.6)

Enterovirus unspecified type (N = 5)

Enterovirus unspecified type (N = 3)

  1. * One of the cases was a two month old with normal CSF (9 WBC & 4000 RBC) and enterovirus unspecified type isolated from site other than CSF
  2. † Sites that reviewed inpatients only