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Table 1 Characteristics of 48 patients with community-acquiredbacterial meningitis and coexisting arthritis*

From: Arthritis in adults with community-acquired bacterial meningitis: a prospective cohort study

Characteristics

Patients (n = 48)

Sex, no. male/no. female

21/27

Age, median years (range)

49 (17–90)

Predisposing factors for bacterial arthritis

 

   Immunodeficiency†

6 (13)

   Preexisting joint pathology‡

3 (6)

   Age ≥ 80 years

4 (8)

Blood culture positive

29/46 (63)

Erythrocyte sedimentation rate – mm/hour, median (range)

45 (5 – 289)

Blood leukocyte count – 109/L, median (range)

18 (4 – 40)

Results of cerebrospinal fluid culture

 

   Neisseria meningitidis

32 (67)

   Streptococcus pneumoniae

11 (23)

   Other bacteria§

5 (10)

Positive synovial fluid culture

6/23 (26)

Arthritis present ≤ 4 days after admission

29 (60)

   Arthritis present on presentation

15 (31)

Time between admission and arthritis, median days (range)

5 (-2 – 12)

Monoarticular arthritis

29 (60)

   Knee

14/29 (48)

   Wrist

5/29 (17)

   Ankle

4/29 (14)

   Other¶

6/29 (21)

Polyarticular arthritis

19 (40)

   Knee

15/19 (79)

Residual joint symptoms in surviving patients$

10/44 (23)

  1. *Data are given as no. of patients with characteristic/no. evaluated (%), unless otherwise indicated.
  2. †alcoholism (n = 1), diabetes mellitus (n = 4) and splenectomy (n = 1).
  3. ‡rheumatoid arthritis (n = 1), gout (n = 1), hip prostheses (n = 1).
  4. § Haemophilus influenzae (n = 2), Escherichia coli (n = 1), group B streptococcus (n = 1) and group G streptococcus (n = 1).
  5. ¶ hip (n = 2), shoulder (n = 2), elbow (n = 2).
  6. $cause of meningitis: N. meningitidis (n = 5), S. pneumoniae (n = 4), group B streptococcus (n = 1).