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Table 1 Characteristics of 48 patients with community-acquiredbacterial meningitis and coexisting arthritis*

From: Arthritis in adults with community-acquired bacterial meningitis: a prospective cohort study

Characteristics Patients (n = 48)
Sex, no. male/no. female 21/27
Age, median years (range) 49 (17–90)
Predisposing factors for bacterial arthritis  
   Immunodeficiency† 6 (13)
   Preexisting joint pathology‡ 3 (6)
   Age ≥ 80 years 4 (8)
Blood culture positive 29/46 (63)
Erythrocyte sedimentation rate – mm/hour, median (range) 45 (5 – 289)
Blood leukocyte count – 109/L, median (range) 18 (4 – 40)
Results of cerebrospinal fluid culture  
   Neisseria meningitidis 32 (67)
   Streptococcus pneumoniae 11 (23)
   Other bacteria§ 5 (10)
Positive synovial fluid culture 6/23 (26)
Arthritis present ≤ 4 days after admission 29 (60)
   Arthritis present on presentation 15 (31)
Time between admission and arthritis, median days (range) 5 (-2 – 12)
Monoarticular arthritis 29 (60)
   Knee 14/29 (48)
   Wrist 5/29 (17)
   Ankle 4/29 (14)
   Other¶ 6/29 (21)
Polyarticular arthritis 19 (40)
   Knee 15/19 (79)
Residual joint symptoms in surviving patients$ 10/44 (23)
  1. *Data are given as no. of patients with characteristic/no. evaluated (%), unless otherwise indicated.
  2. †alcoholism (n = 1), diabetes mellitus (n = 4) and splenectomy (n = 1).
  3. ‡rheumatoid arthritis (n = 1), gout (n = 1), hip prostheses (n = 1).
  4. § Haemophilus influenzae (n = 2), Escherichia coli (n = 1), group B streptococcus (n = 1) and group G streptococcus (n = 1).
  5. ¶ hip (n = 2), shoulder (n = 2), elbow (n = 2).
  6. $cause of meningitis: N. meningitidis (n = 5), S. pneumoniae (n = 4), group B streptococcus (n = 1).