Table 2 Efficacy and tolerability of the different drugs used in 415 patients with Mediterranean spotted fever.
From: Mediterranean spotted fever: clinical and laboratory characteristics of 415 Sicilian children
Chloramphenicol n = 107 | Clarithromycin n = 230 | Azithromycin n = 78 | p | |
|---|---|---|---|---|
Mean time to defervescence (h) | 40.62 | 41.94 | 47.13 | 0.093 |
Hospitalization mean (days) | 5.4 | 3.4 | 4.1 | 0.018 |
Prolonged fever / relapse (%) | 0 | 2 (0.9) | 9 (11.5) | < 0.01 |
Side effects requiring drug discontinuation (%) | 0 | 16 (7) | 1 (1.3) | < 0.01 |