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Table 3 Results of logistic regression models predicting overall change in blood CD4 cell count during ART. Responses are defined as either (i) the risk of immunological non-response (an increase of <50 cells/μl) or (ii) failure to attain an absolute CD4 cell count of ≥ 200 cells/μl after 48 weeks ART.

From: CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Saharan Africa

   Risk of immumological non-respouse at 48 weeks Risk of failure to attain CD4 cell count of ≥ 200 cells/μl at 48 weeks
   OR (95% CI) P value OR (95% CI) P value
Age (years) <30    1.0 1.0   
  30–39 3.15 (1.09, 9.15) 0.035 1.34 (0.66, 2.72) 0.41
  >40 3.88 (1.13, 13.39) 0.032 3.52 (1.55, 7.99) 0.003
Sex Female 1.0      
  Male 0.42 (0.13, 1.39) 0.16 1.73 (0.90, 3.35) 0.10
Baseline CD4 count >150 1.0    1.0   
  100–149 0.63 (0.23, 1.72) 0.37 2.49 (0.89, 6.96) 0.08
  50–99 0.18 (0.05 0.70) 0.013 5.97 (2.29, 15.58) <0.001
  <50 0.18 (0.05, 0.72) 0.016 12.11 (4.43, 33.14) <0.001
WHO clinical stage 1 & 2 1.0    1.0   
  3 1.12 (0.37, 3.40) 0.84 1.32 (0.54, 3.26) 0.54
  4 2.11 (0.63, 7.03) 0.22 1.19 (0.45, 3.17) 0.72
Baseline viral load <5 log10 1.0    1.0   
  >5 log10 0.21 (0.07, 0.66) 0.008 0.47 (0.26, 0.86) 0.014
Follow-up viral load <400 all visits 1.0    1.0   
  >400 any visit 4.25 (1.30, 13.87) 0.017 3.00 (1.14, 7.90) 0.026