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Figure 5 | BMC Infectious Diseases

Figure 5

From: Neutropenia induced in outbred mice by a simplified low-dose cyclophosphamide regimen: characterization and applicability to diverse experimental models of infectious diseases

Figure 5

Comparison of bacterial growth of three human pathogens in the lungs of neutropenic mice inoculated by nasal instillation of S. aureus ATCC 29213 and S. pneumoniae INS-E611 or aerosolized K. pneumoniae GRP-0107. The apparent difference in the extension of the growth curves is due to the fact that mice infected with pneumococci survived the model, while the other organisms killed the animals 24–48 hours after infection; other details for each model in the text.

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