Table 4 Clinical parameters, antimicrobial regimens and treatment outcome of patients with bloodstream infection (BSI) due to PER-1-positive P. aeruginosa (PER-1-Pa) isolates
Isolate | Age (yr) | Sex a | McCabe & Jackson b | Charlson weighted index | Primary source(s) of infection c | Severity of septicemia | Empirical treatment | Treatment administered after ID and AST d results | Treatment outcome e | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Agent (daily dose) | Adequate | Agent (daily dose) | Timing from BSI onset | Duration (days) | Â |
338/98 | 58 | M | NF | 1 | Unknown | Severe sepsis | SXT (10 ml × 3) | No | AMK (0.5 g × 2) FEP (2 g × 3) | Day 4 Day 7 | 10 11 | FA |
LS034/99 | 60 | M | NF | 0 | LRTI | Severe sepsis | IPM (1.5 g × 3) | No | IPM (1.5 g × 3) AMK (0.5 g × 2) | Day -21 Day -2 | 53 8 | RE |
140/99 | 69 | M | NF | 1 | Unknown | Severe sepsis | CTX (2 g × 3) IPM (0.5 g × 3) | No | Not changed | Day -15 Day 0 | 20 5 | FA |
47/00 | 19 | F | NF | 6 | LRTI, IVC | Sepsis | MEM (1 g × 2) AMK (1 g) | Yes | MEM (1 g × 3) AMK (1 g) | Day 1 | 6 18 | FA |
324/00 | 27 | M | NF | 0 | Unknown | Sepsis | CIP (0.4 g × 2) | No | Not changed | Day 0 | 13 | RE |
A360/00 | 72 | M | RF | 6 | LRTI | Sepsis | None | No | MEM (0.5 g × 4) AMK (0.75 g) | Day 3 Day 3 | 13 18 | RE |
527/00 | 60 | M | NF | 3 | Unknown | Sepsis | IPM (0.5 g × 4) | No | Not changed | Day -9 | 13 | CR |
2126/01 | 67 | F | RF | 6 | UTI | Sepsis | CRO (2 g) | No | IPM (1 g × 3) | Day 3 | 8 | PR |
A150/02 | 90 | M | UF | 3 | UTI | Severe sepsis | CIP (0.2 g × 2) TZP (2 g × 2) | No | IPM (0.5 g × 2) | Day 1 | 11 | RE |