Table 3 Clinical parameters of investigated BSI cases (n = 24) due to ceftazidime-resistant P. aeruginosa strains: difference between PER-1-positive (PER-1-Pa) and ESBL-negative (ESBL-N-Pa) isolates.a
Clinical parameters | PER-1-Pa | ESBL-N-Pa | P value b |
|---|---|---|---|
No. BSI episodes | 9 | 15c | - |
Severity of septicemia | Â | Â | Â |
   - Sepsis | 5 (55.6) | 12 (80.0) | NS |
   - Severe sepsis | 4 (44.4) | 1 (6.7) | 0.03 |
   - Septic shock | 0 (0.0) | 2 (13.3) | NS |
Empirical treatment provided | 8 (88.9) | 14 (93.3) | NS |
   - Adequate | 1 (11.1) | 9 (60.0) | 0.02 |
Adequate treatment after ID / AST d results | 1 (11.1) | 12 (80.0) | < 0.01 |
Predisposing factors for BSI infection | Â | Â | Â |
   - Bladder catheter | 9 (100) | 7 (46.7) | 0.01 |
   - Previous use of antibiotics | 8 (88.9) | 9 (60.0) | NS |
   - Intravascular catheter | 9 (100) | 7 (46.7) | 0.01 |
   - Immunosuppressive therapy | 5 (55.6) | 5 (33.3) | 0.04 |
   - Previous surgery | 7 (77.8) | 5 (33.3) | NS |
   - Drainages | 2 (22.2) | 5 (33.3) | NS |
   - Mechanical ventilation | 6 (66.7) | 3 (20.0) | 0.03 |
   - Esophagogastroscopy | 1 (11.1) | 2 (13.3) | NS |
   - Other | 4 (44.4) e | 4 (26.6) f | - |
Overall secondary BSI | 5 (55.6) | 10 (66.7) | NS |
   - Urinary tract | 2 (22.2) | 3 (20.0) | NS |
   - Respiratory tract | 3 (33.3) | 4 (26.7) | NS |
   - IV catheter | 1 (11.1) | 1 (6.7) | NS |
   - Wounds | 0 (0.0) | 4 (26.7) | NS |