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Table 1 Major demographic features, predisposing conditions, antifungal treatment and outcome for patients with candidaemia and solid tumours or haematological malignancies (univariate analysis).

From: Candidaemia and cancer: patients are not all the same

Variables Solid (%) Haematological (%) p value
Demographic factors    
   Age (median, years) 54.2 14.7 0.007c
   Male sex 51.6 68.4 0.194a
   Nosocomial infection 89.1 89.5 1.000b
Predisposing conditions    
   Neutropenia 22.2 78.9 < 0.001a
   Duration of neutropenia (median, days) 5.0 17.0 0.004c
   Mucositis 9.4 11.1 1.000b
   Diarrhoea 29.7 21.1 0.460a
   Ileus 34.4 5.6 0.016a
   Corticosteroids 41.3 84.2 0.001a
   Chemotherapy 29.4 84.2 < 0.001a
   Previous stay in the intensive care unit 48.4 21.1 0.034a
Invasive medical procedures    
   Central venous catheter 75.0 89.5 0.221b
   Implanted port 25.0 36.8 0.311a
   Mechanical ventilation 35.9 0.0 0.002a
   Urinary catheter 59.4 10.5 < 0.001a
   Parenteral nutrition 21.9 5.3 0.172b
   Haemodialysis 4.7 5.3 1.000b
   Radiotherapy 9.4 5.3 1.000b
   Major surgery 42.2 0.0 0.001a
   Gastrointestinal surgery 23.4 0.0 0.018b
Antibiotic use    
   Duration (median, days) 13 15 0.996c
   Number of antibiotics (median) 3 3 0.474c
   Metronidazole or clindamycin 42.2 15.8 0.035a
   4th generation cephalosporins 29.7 68.4 0.003a
   Glycopeptides 37.5 57.9 0.114a
   Carbapenems 12.5 15.8 0.708b
Breakthrough candidaemia 7.8 15.6 0.376b
Previous bactaeremia 28.1 47.4 0.116a
Antifungal treatment 73.4 84.2 0.542b
Death during hospitalization 53.1 36.8 0.213a
Total (n) 64 19 83
  1. a Chi-square test; b Fisher's exact test; c Mann-Whitney test.