Asymptomatic bacteriuria in sickle cell disease: a cross-sectional study

BMC Infectious Diseases

Table 2 Clinical characteristics of enrolled subjects with confirmed ASB and sterile urine (N = 248)*

Clinical characteristics	Confirmed ASB N = 14	Sterile urine N = 234
Age yr	27.9 ± 2.3	26.4 ± 2.5
†Gender (M:F)	1:13	124:110
#Genotype frequency (HbSS:HbSC:HbSβ⁰:HbSβ⁺: sickle variants)	9:2:1:2:0	130:75:5:19:5
Creatinine μmol/L	49.1 ± 12.4	53.7 ± 14.3
Uric Acid mmol/L	0.36 ± 0.29	0.33 ± 0.08
†Proteinuria ≥ trace : No proteinuria (n = 168)	1:7	22 :138
†Positive History of gram negative sepsis	1	1
†Positive recorded history of ever having UTI	7	25
†Cumulative number of recorded clinic visits for symptomatic UTI*	18	49

*Values of subjects with probable ASB excluded from table. † Values are counts. Abbreviations : ASB = asymptomatic bacteriuria; HbSC= Sickle cell-haemoglobin C, HbSβ⁰ = Sickle cell-β⁰ thalassemia, HbSβ⁺ = Sickle cell-β⁺ thalassemia; UTI = Urinary Tract Infections
#Sickle variants include sickle cell-hereditary persistence of foetal haemoglobin, sickle cell -haemoglobin O Arab, sickle cell -haemoglobin Lepore-Boston;

ISSN: 1471-2334