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Table 3 Comparative bacterial load and pathology scores of tissues between groups of treatment of animals that died after bacterial challenge.

From: Clarithromycin is an effective immunomodulator when administered late in experimental pyelonephritis by multidrug-resistant Pseudomonas aeruginosa

  A (controls) B (clarithromycin) C (amikacin) D (clarithromycin + amikacin)
  Bacterial load (mean ± SE, log10 of cfu/mL)
Liver 3.46 ± 0.79 3.34 ± 0.89 4.19 ± 0.92 2.14 ± 0.59
Spleen 3.64 ± 0.75 3.63 ± 0.92 4.10 ± 0.90 3.58 ± 0.79
Kidney 5.94 ± 0.50 4.92 ± 0.73 6.63 ± 0.30 6.82 ± 0.12
Lung 4.73 ± 0.59 4.09 ± 0.83 6.28 ± 0.39 5.76 ± 0.62
  Pathology score (mean ± SE)
Liver 1.25 ± 0.25 0.38 ± 0.18a 0.80 ± 0.20 0.71 ± 0.28
Spleen 2.50 ± 0.38 2.70 ± 0.37 2.80 ± 0.20 2.43 ± 0.37
Kidney 2.38 ± 0.46 2.13 ± 0.52 2.30 ± 0.58 2.71 ± 0.36
Lung 1.38 ± 0.32 0.75 ± 0.25b 1.30 ± 0.16 1.29 ± 0.29
  1. P of comparisons to group A: a0.012, b0.049