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Table 3 Comparative bacterial load and pathology scores of tissues between groups of treatment of animals that died after bacterial challenge.

From: Clarithromycin is an effective immunomodulator when administered late in experimental pyelonephritis by multidrug-resistant Pseudomonas aeruginosa

 

A (controls)

B (clarithromycin)

C (amikacin)

D (clarithromycin + amikacin)

 

Bacterial load (mean ± SE, log10 of cfu/mL)

Liver

3.46 ± 0.79

3.34 ± 0.89

4.19 ± 0.92

2.14 ± 0.59

Spleen

3.64 ± 0.75

3.63 ± 0.92

4.10 ± 0.90

3.58 ± 0.79

Kidney

5.94 ± 0.50

4.92 ± 0.73

6.63 ± 0.30

6.82 ± 0.12

Lung

4.73 ± 0.59

4.09 ± 0.83

6.28 ± 0.39

5.76 ± 0.62

 

Pathology score (mean ± SE)

Liver

1.25 ± 0.25

0.38 ± 0.18a

0.80 ± 0.20

0.71 ± 0.28

Spleen

2.50 ± 0.38

2.70 ± 0.37

2.80 ± 0.20

2.43 ± 0.37

Kidney

2.38 ± 0.46

2.13 ± 0.52

2.30 ± 0.58

2.71 ± 0.36

Lung

1.38 ± 0.32

0.75 ± 0.25b

1.30 ± 0.16

1.29 ± 0.29

  1. P of comparisons to group A: a0.012, b0.049