Table 2 Characteristics of patients according to ESBL-producing K. pneumoniae BSI from January 1996 to May 2001.
Variables | ESBL (n = 56) | Non-ESBL (n = 52) | |||
|---|---|---|---|---|---|
N | % | N | % | P | |
AGE (infants) | |||||
<1 year | 17 | 54.8 | 14 | 45.2 | 0.693 |
≥ 1 year | 39 | 50.6 | 38 | 49.4 | |
AGE (elderly) | |||||
>60 years | 11 | 57.9 | 8 | 42.1 | 0.561 |
< = 60 years | 45 | 50.6 | 44 | 49.4 | |
SEX | |||||
Male | 25 | 47.2 | 28 | 52.8 | 0.339 |
Female | 31 | 56.4 | 24 | 43.6 | |
HOSPITAL LOCATION | |||||
ICU | 31 | 63.3 | 18 | 36.7 | 0.031 |
Other units | 25 | 42.4 | 34 | 57.6 | |
HOSPITAL STAY (days) | |||||
>10 days | 50 | 56.2 | 39 | 43.8 | 0.051 |
< = 10 days | 6 | 31.6 | 13 | 68.4 | |
CENTRAL VENOUS CATHETER | |||||
0 | 29 | 44.6 | 36 | 55.4 | 0.044 |
1 | 23 | 60.5 | 15 | 39.5 | |
≥ 2 | 4 | 80.0 | 1 | 20.0 | |
SWAN-GANZ | |||||
Yes | 2 | 66.7 | 1 | 33.3 | 1.000 |
No | 54 | 51.4 | 51 | 48.6 | |
HEMODIALYSIS | |||||
Yes | 4 | 66.7 | 2 | 33.3 | 0.680 |
No | 52 | 51.0 | 50 | 49.0 | |
URINARY CATHETER | |||||
Yes | 11 | 68.8 | 5 | 31.3 | 0.143 |
No | 45 | 48.9 | 47 | 54.0 | |
MECHANICAL VENTILATION | |||||
Yes | 16 | 76.2 | 5 | 23.8 | 0.013 |
No | 40 | 46.0 | 47 | 54.0 | |
DRAINAGE TUBES | |||||
Yes | 5 | 83.3 | 1 | 16.7 | 0.207 |
No | 51 | 50.0 | 51 | 50.0 | |
PREVIOUS ANTIBIOTICS | |||||
0 | 15 | 31.3 | 33 | 68.8 | 0.276 |
1 | 17 | 73.9 | 6 | 26.1 | |
2 | 14 | 56.0 | 11 | 44.0 | |
≥ 3 | 10 | 83.3 | 2 | 16.7 | |
McCabe CLASSIFICATION | |||||
Rapidly fatal | 9 | 52.9 | 8 | 47.1 | 0.623 |
Potentially fatal | 6 | 37.5 | 10 | 62.5 | |
Non fatal | 41 | 54.7 | 34 | 45.3 | |
NUMBER OF COMORBIDITIES | |||||
None | 19 | 51.4 | 18 | 48.6 | 0.662 |
1 | 20 | 47.6 | 22 | 52.4 | |
2 | 14 | 58.3 | 10 | 41.7 | |
3 | 3 | 75.0 | 1 | 25.0 | |
4 | 0 | - | 1 | 100.0 | |
SOURCE OF BSI | |||||
Respiratory | 23 | 56.1 | 18 | 43.9 | 0.343 |
Abdominal | 12 | 42.9 | 16 | 57.1 | |
Urinary | 8 | 66.7 | 4 | 33.3 | |
Catheter | 6 | 40.0 | 9 | 60.0 | |
CNS | 3 | 75.0 | 1 | 25.0 | |
Wound | 2 | 100.0 | 0 | - | |
Abdominal | 12 | 42.9 | 16 | 57.1 | |
Others | 2 | 33.3 | 4 | 66.7 | |
SEPTIC SHOCK | |||||
Yes | 10 | 45.5 | 12 | 54.5 | 0.501 |
No | 46 | 53.5 | 40 | 46.5 | |
PLATELETS | |||||
≥ 80,000/mm3 | 31 | 50.8 | 30 | 49.2 | 0.438 |
<80,000/mm3 | 15 | 32.6 | 10 | 25.0 | |
ANTIBIOTIC THERAPY | |||||
Adequate | 33 | 47.8 | 36 | 52.2 | 0.265 |
Inadequate | 23 | 41.1 | 16 | 30.8 | |
15 DAY-MORTALITY | |||||
Yes | 18 | 69.2 | 8 | 30.8 | 0.042 |
No | 38 | 46.3 | 44 | 53.7 | |
TIME TRENDS IN MORTALITY | |||||
1996–1998 | 21 | 55.3 | 17 | 44.7 | 0.601 |
1999–2001 | 35 | 50.0 | 35 | 50.0 | |