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Table 1 Evolution of hematological detection in experimental leptospirosis in guinea pigs (n = 8 in each group), data are presented as mean ± SD. (*P < 0.05, compare with control)

From: Thrombocytopenia in the experimental leptospirosis of guinea pig is not related to disseminated intravascular coagulation

Characteristics

Control

24 h after infection

48 h after infection

72 h after infection

96 h after infection

Platelet count (109/L)

564 ± 82

352 ± 40*

307 ± 50*

97 ± 35*

30 ± 14*

MPV (fL)

6.31 ± 0.19

6.53 ± 0.51

6.51 ± 0.18

7.04 ± 0.51*

8.09 ± 0.33*

11-DH-TXB2 (μg/L)

3.51 ± 0.55

5.12 ± 0.73*

4.85 ± 0.86*

5.31 ± 1.31*

7.46 ± 1.67*

TM (μg/L)

2.91 ± 0.30

3.40 ± 0.41*

5.63 ± 0.57*

6.62 ± 0.49*

6.87 ± 0.62*

TAT (μg/L)

3.66 ± 0.66

2.87 ± 1.01

3.27 ± 1.56

2.32 ± 0.77*

2.04 ± 0.25*

D-dimer (mg/L)

0.13 ± 0.01

0.19 ± 0.06*

0.24 ± 0.02*

0.27 ± 0.05*

0.19 ± 0.04*

FDPs (mg/L)

2.01 ± 0.08

1.99 ± 0.07

2.70 ± 0.53*

3.20 ± 0.43*

2.60 ± 0.56*