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Table 2 Results of Efficacy.

From: A randomized, parallel study of the safety and efficacy of 45 mg primaquine versus 75 mg bulaquine as gametocytocidal agents in adults with blood schizonticide-responsive uncomplicated falciparum malaria [ISCRTN50134587]

Days of follow -up No of patients positive for gametocytes Patients sample positive for exflagellation
  Pts treated with PQ
N = 31
Pts treated with BQ
N = 59
Pts treated with PQ
N = 31
Pts treated with BQ
N = 59
1 31/31
100%
59/59
100%
31/31
100%
59/59
100%
4 31/31
100%
59/59
100%
31/31
100%
59/59
100%
8 20/31 *
65%
19/59 *
32%
16/31 *
52%
7/59 *
12%
15 Nil Nil Nil Nil
22 Nil Nil Nil Nil
29 Nil Nil Nil Nil
  1. * statistically significant P < 0.05
  2. Acknowledgements: This study was carried out as a project under the Center for Advanced Research in Clinical Pharmacology, and was funded by the Indian Council of Medical Research, New Delhi. We thank Nicholas Piramal India Ltd for the supply of bulaquine capsules.