Table 1 Demographic, epidemiological, clinical, and laboratory features of study patients
From: Clinical and epidemiological predictors of transmission in Severe Acute Respiratory Syndrome (SARS)
Demographics | n | (%) |
|---|---|---|
Age | Â | Â |
- < = 24 | 23 | 23.5% |
- 25 to 49 | 61 | 62.2% |
- 50 and above | 14 | 14.3% |
Female gender | 79 | 80.6% |
Non-Chinese ethnicity | 40 | 40.8% |
Epidemiological features | n | (%) |
Context of exposure to SARS | Â | Â |
- healthcare worker | 57 | 58.2% |
- hospital inpatient | 10 | 10.2% |
- *others | 31 | 31.6% |
Date of onset | Â | Â |
- 21/3/03 or earlier (before universal PPE) | 78 | 79.6% |
- 22/3//03 or later (after universal PPE) | 20 | 20.4% |
Delayed isolation (on Day 7 or later) | 34 | 34.7% |
Ever admitted to a non-isolation ward | 12 | 12.2% |
Ever admitted to a non-isolation ward | 12 | 12.2% |
Clinical features | n | (%) |
Chronic illness | Â | Â |
- chronic respiratory illness | 7 | 7.1% |
- disease with immunosuppression | 10 | 10.2% |
Disease severity at time of isolation | Â | Â |
- had an abnormal chest radiograph | 78 | 79.6% |
- required oxygen therapy | 14 | 14.3% |
- admitted to intensive care or high dependency | 4 | 4.1% |
- intubated | 2 | 2.0% |
Signs and symptoms at time of isolation | Â | Â |
- temperature > = 38°C | 74 | 75.5% |
- fever | 95 | 96.9% |
- cough | 55 | 56.1% |
- dyspnoea | 24 | 24.5% |
- vomiting | 17 | 17.3% |
- diarrhoea | 14 | 14.3% |
Chest radiograph and confirmatory tests for SARS | Â | Â |
- ever had abnormal CXR | 88 | 89.8% |
- positive PCR specimen | 13 | 13.3% |
- positive serology | 91 | 92.9% |
^Other laboratory investigations | Median | (IQR) |
- highest alanine aminotransferase (7–36 IU/L) | 21 | (14–41) |
- highest lactate dehydrogenase (200–500 IU/L) | 447 | (348–650) |
- lowest platelet count (160-390*10^9/L) | 184 | (145–220) |
- highest neutrophil count (4-10*10^9/L) | 3.36 | (2.35–5.04) |
- lowest lymphocyte count (1.5-4.3*10^9/L) | 0.93 | (0.66–1.21) |