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Table 1 Decreased anti-HIV-1 activity of polymeric candidate microbicides in the presence of human seminal plasma

From: Role of seminal plasma in the anti-HIV-1 activity of candidate microbicides

Polymer HIV-1 IIIB HIV-1 BaL
  ED50 μg/ml ED50SP μg/ml ED50SP: ED50 ratio ED50 μg/ml ED50SP μg/ml ED50SP: ED50 ratio
Poly (naphthalene sulfonate) 1.1 17.3 15.7 37.5 141 3.8
Cellulose sulfate 1.6 64.7 40.4 7.1 401 56.5
Carrageenan 1.4 63.4 45.6 6.3 149 23.7
Cellulose acetate 1,2-benzenedi-carboxylate 1.0 72.7 72.7 9.8 141 14.4
Polystyrene sulfonate 2.2 36.1 16.4 12.8 389 30.4
  1. SP = seminal plasma added