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Table 2 Effectiveness of influenza vaccines in HIV-infected patients

From: Efficacy and clinical effectiveness of influenza vaccines in HIV-infected individuals: a meta-analysis

Study Outcome Studied Vaccine Control Risk Difference (95% C.I.) NNV* Vaccine effectiveness **
Tasker 1999 [26] Symptoms of respiratory illness, at least 4 fold increase in antibody titre, viral culture 16/55 23/47 -0.198 (-0.387, -0.01) 5 41%
Fine 2001, [4] Influenza like illness or a 4 fold increase in antibody titers or isolation of influenza virus 19/42 18/29 -0.168 (-0.404, -0.067) 6 27%
Raineri 2005, [34] Influenza illness 12/90 34/55 -0.485 (-0.632, -0.337) 3 78%
Yamanaka 2005, [27] Influenza like symptoms with at least 4 fold increase in antibody titre or viral isolation in culture 16/262 14/66 -0.151 (-0.255, -0.048) 7 71%
  1. C.I.: Confidence Interval; NNV: * Number needed to vaccinate (= 1/RD); ** Vaccine effectiveness = 100*(1-risk ratio)