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Table 1 Characteristics of studies evaluating the effectiveness of influenza vaccine in HIV infected Individuals

From: Efficacy and clinical effectiveness of influenza vaccines in HIV-infected individuals: a meta-analysis

Study, location and reference

Number of Patients

Study Design

Age * (years)

CD4 Cell Count**

Vaccine strains

 

Comparator

Tasker 1999, USA, [26]

102

Randomized double blind, placebo controlled

33

403.1

A/Johannesburg/33/94 A/Texas/36/91 B/Harbin/07/94)

(H3N2), (HlNl),

Saline

Fine 2001, USA, [4]

71

Outbreak investigation

38

149

A/Nanchang/933/95(H3N2), A/Texas/36/91(H1N1), B/Harbin/07/94, York/83/97(H3N2)

A/New

None

Raineri 2005, Italy, [34]

145

Prospective nonrandomized

20–69

--

INFLEXAL V, Berna

 

None

Yamanaka 2005, Japan, [27]

328

Prospective nonrandomized

40.8

379

A/New Caledonia/20/99 A/Panama/2007/99 B/Shanton/7/87

(H1N1), (H3N2),

None

  1. *- mean or range; **-median values (mean used when median was not reported[26])