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Table 5 Outcome and surgical treatment of injection drug users and nonaddicts with Staphylococcus aureus endocarditis.

From: Clinical manifestations and outcome in Staphylococcus aureus endocarditis among injection drug users and nonaddicts: a prospective study of 74 patients

 

Injection drug users

Nonaddicts

Total

 

Outcome

(n = 20)

(n = 54)

(n = 74)

P

Case fatality rate

    

   At 7 days

1 (5)

6 (11)

7 (9)

0.67

   At 28 days

1 (5)

16 (30)

17 (23)

0.03

   At 3 months

2 (10)

21 (39)

23 (31)

0.02

Duration of fever, median days (IQR)a

3 (2–10)

3 (0–6)

3 (1–6)

0.24

Duration of hospitalization, median days (IQR)

32 (30–48)

32 (20–47)

32 (24–47)

0.55

Cardiac surgery

3 (15)

4 (7)

7 (9)

0.38

   Valve replacement

1 (5)

4 (7)

5 (7)

1.00

   Valve repairb

3 (15)

0 (0)

3 (4)

0.02

  1. NOTE. Data are no. (%) of patients, unless otherwise indicated. IQR, interquartile range.
  2. a Fever > 37.5°C after the first positive blood culture for S. aureus with 72 patients (2 patients excluded, death before defervescence).
  3. b Includes 2 patients with vegetectomy and 1 patient with annuloplasty.