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Table 1 The pattern recognition receptors (PRRs), which recognize C. trachomatis pathogen-associated molecular patterns (PAMPs), and the single nucleotide polymorphisms (SNPs) studied

From: Do host genetic traits in the bacterial sensing system play a role in the development of Chlamydia trachomatis-associated tubal pathology in subfertile women?

PRR PAMP SNP
TLR9 CpG-rich motifs -1237 T>C and +2848 G>A
TLR4 LPS and HSP +896 A>G
CD14 LPS and HSP (co-receptor of TLR4) -260 C>T
CARD15/NOD2 Peptidoglycans Leu1007fsinsC (SNP13)
  1. TLR = toll-like receptor; CD = cluster of differentiation; CARD = caspase recruitment domain; NOD = nucleotide oligomerisation domain; CpG = cytosine-phosphate-guanine; LPS = lipopolysaccharide; HSP = heat shock protein; T = thymine; C = cytosine; G = guanine; A = adenine; Leu = leucine-rich repeat domain; fsins = frameshift insertion.