Figure 3

Immunophenotypic changes in lymph nodes from patients with HME. Note the marked expansion of CD8 cells in the medullary and paracortical regions (a) not observed in the control lymph node from a patient with bacterial bronchopneumonia (b). Although not quantitatively different, CD68 macrophages were more clustered within the medullary sinuses and paracortical regions in lymph nodes from HME patients (c) compared with the marginal distribution observed in a control lymph node from a patient with bacterial bronchopneumonia (d) (Immunoperoxidase with hematoxylin counterstain; original magnifications 20×).