Figure 4From: Synergistic effect of interleukin 1 alpha on nontypeable Haemophilus influenzae-induced up-regulation of human beta-defensin 2 in middle ear epithelial cellsRegulation of the synergistic activity via the p38 MAP kinase pathway. Real time quantitative PCR shows that SB203580 (10 and 20 uM) blocks the synergistic effect of IL-1α and NTHi lysate, but PD98059 (10 and 20 uM) does not. Values are given as the mean ± standard deviation. N = 3. *: p < 0.05, **: p < 0.01. DMSO: dimethylsulfoxide.Back to article page