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Table 1 Clinical and demographic characteristics of the study groups.

From: Oxidative stress in hepatitis C infected end-stage renal disease subjects

Study Groups HCV (+) HD subjects HCV (-) HD subjects Control subjects
N 16 24 24
Age (year) 50.3 ± 10 46.8 ± 8.5 40.4 ± 7.3
Gender (M/F) 10/6 13/11 14/10
Uric Acid (mg/dL) 5.5 ± 1.5* 5.54 ± 1.25* 4.4 ± 0.3
BUN (mg/dL) 61 ± 23* 65 ± 31* 16 ± 5.5
ALT 27 ± 13.7 22.4 ± 10.7 23.3 ± 4.8
Creatinine (mg/dL) 6.05 ± 2.4* 7.01 ± 1.5* 0.97 ± 0.15
HCV-RNA (log copies/mL) 4.9 ± 0.7 -- --
DD (Years) 4.25 ± 2.5 3.35 ± 2.7 --
TAC ( mmol Trolox eq./L) 1.27 ± 0.2 1.68 ± 0.4 2.1 ± 0.6**
TP (micromole H2O2/L) 12.9 ± 6.1** 10.9 ± 6.9** 5.2 ± 2.1
OSI (%) 1.6 ± 0.6** 1.1 ± 0.9** 0.3 ± 0.1
  1. Data were presented as mean ± SD.
  2. *p < 0.05 vs. controls.
  3. **p < 0.05/3 vs. HD subjects with or without HCV infection.
  4. ***p < 0.05/3 vs. controls.
  5. M, male; F, female; DD, dialysis duration; BUN, blood urea nitrogen; HD, hemodialysis;
  6. HCV, hepatitis C virus; ALT, alanine aminotransferase; TAC, total antioxidant capacity; TP, total peroxide level; OSI, oxidative stress index.