Table 1 Comparison of receptor expressions of neutrophils and monocytes in patients with Streptococcus pneumoniae, influenza A and aetiologically undefined pneumonia. P values for overall group differences tested using analysis of variance (ANOVA).
From: Measurement of complement receptor 1 on neutrophils in bacterial and viral pneumonia
Parameter | A S. pneumoniae (n = 13) | B Influenza A (n = 13) | C Undefined (n = 37) | D Control (n = 63) | p value |
|---|---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | ||
WBC (×109/l) | 12.3 (6.9) | 7.6 (2.2) | 10.3 (4.2) | 4.8 (1.3) | <0.0001 |
PMNL (×109/l) | 8.9 (4.4) | 5.5 (2.3) | 7.5 (3.6) | 2.6 (0.9) | <0.0001 |
CRP (mg/l) | 370.0 (121.5) | 108.2 (87.7) | 179.7 (94.4) | - | <0.0001 |
ESR (mm/h) | 79.4 (20.4) | 39.1 (29.7) | 69.2 (24.1) | - | 0.0018 |
Receptor expression of neutrophils | |||||
CR1 | 20.4 (9.8) | 7.5 (4.6) | 19.3 (8.8) | 6.3 (2.2) | <0.0001 |
CR3 | 63.1 (32.6) | 80.7 (40.9) | 107.2 (47.9) | 48.5 (17.8) | <0.0001 |
FcγRI | 4.7 (2.5) | 2.9 (2.5) | 5.0 (5.3) | 0.6 (0.3) | <0.0001 |
FcγRII | 12.8 (5.4) | 10.3 (4.2) | 13.0 (4.3) | 11.0 (1.8) | 0.0350 |
FCγRIII | 89.6 (43.3) | 111.7 (46.2) | 120.3 (43.1) | 128.0 (34.3) | 0.0285 |
Receptor expression of monocytes | |||||
CR1 | 11.7 (4.5) | 9.7 (5.0) | 15.3 (6.7) | 4.6 (2.7) | <0.0001 |
CR3 | 63.9 (30.8) | 84.6 (30.4) | 109.8 (65.1) | 44.6 (33.5) | <0.0001 |
FcγRI | 14.0 (3.7) | 18.9 (4.5) | 18.9 (8.7) | 8.4 (1.9) | <0.0001 |
FcγRII | 13.1 (6.4) | 18.5 (6.9) | 18.7 (8.2) | 11.7 (1.9) | <0.0001 |