Tuberculosis associated with Mycobacterium tuberculosisBeijing and non-Beijing genotypes: a clinical and immunological comparison

Table 3 Clinical and chest X-ray manifestations of patients by M. Tuberculosis genotypes

Parameters	Beijing n = 21 (%)	Non-Beijing n = 20 (%)	Univariate analysis
			OR (95% CI)	p value
Clinical presentations
Cough	18 (85.7)	20 (100)	0.00 (0.00–1.27)	0.125
Median duration (range)^a	60 (14–1440)	30 (2–180)		0.048
Fever	9 (42.9)	17 (85.0)	0.13 (0.03–0.57)	0.005
Haemoptysis	4 (19.0)	6 (30.0)	0.55 (0.14–2.22)	0.414
Weight loss	16 (76.2)	12 (60.0)	2.13 (0.58–7.87)	0.265
Appetite loss	6 (28.6)	4 (20.0)	1.60 (0.40–6.39)	0.523
Night sweats	2 (9.5)	7 (35.0)	0.20 (0.04–0.99)	0.049
Chest pain	2 (9.5)	4 (20.0)	0.42 (0.08–2.29)	0.343
CXR presentations
Unilateral disease	7 (33.3)	8 (40.0)	0.75 (0.22–2.61)	0.658
Bilateral disease	13 (61.9)	11 (55.0)	1.33 (0.39–4.52)	0.654
Pleural effusion	1 (4.8)	1 (5.0)	0.95 (0.09–9.75)	0.972
Cavity	2 (9.5)	7 (35.0)	0.20 (0.04–0.99)	0.049
WBC count (cells/μl)
Total WBC (mean ± SD)	8629 ± 3331	10415 ± 3996		0.150
Lymphocytes (mean ± SD)	1376 ± 614	1563 ± 983		0.496
Monocytes (mean ± SD)	656 ± 340	901 ± 361		0.014
Eosinophils (mean ± SD)	144 ± 194	80 ± 82		0.193
Basophils (mean ± SD)	32 ± 17	40 ± 43		0.474
Anemia^b	14 (66.7)	13 (65.0)	1.08 (0.31–3.81)	0.910
Hemoglobin (g/dL)
Male (mean ± SD)	11.8 ± 1.2	11.3 ± 1.6
Female (mean ± SD)	11.6 ± 1.9	11.3 ± 1.4

Beijing, Beijing genotype; non-Beijing, non-Beijing genotypes; OR, odds ratio; CI, confidence interval; CXR, chest X-ray; WBC, white blood cells; SD, standard deviation.
^aUnit is in day.
^bHemoglobin < 13 g/dL in males and < 11.8 g/dL in females.

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