Longitudinal follow-up of four subjects presenting with new-onset or progressing ADC. The upper panel of each pair shows the plasma and CSF VL responses along with CSF WBC changes, and the lower panels show treatment effects on the QNPZ-4 scores and the blood CD4 counts. The table below each graph indicates clinical features of each respective subject. Antiretroviral medications considered able to penetrate the CSF  are indicated in bold font. The key to the symbols for all graphs are shown to the left of panel set (A).