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Table 1 Distribution of serotypes, PFGE patterns and antimicrobial susceptibility profiles of 34 isolates of S. pnuemoniae isolates from 32 children attending a kindergarten in Kaohsiung, Taiwan

From: High carriage rate of high-level penicillin-resistant Streptococcus pneumoniaein a Taiwan kindergarten associated with a case of pneumococcal meningitis

Isolatea

Serotype

PFGE typeb

MIC (ug/ml) of:c

   

PEN

AUG

FRX

CRO

FTX

FEP

MEM

CHL

ERY

LEV

LID

SXT

P151a

19F

A2

4

4

>4

2

2

4

1

8

>2

1

1

>4

P154a

19F

A2

4

4

>4

2

2

4

1

8

>2

1

1

>4

P156a

19F

A2

4

4

>4

2

2

4

1

4

>2

1

1

>4

P174

19F

A1

2

≤2

4

1

1

0.5

0.5

8

>2

1

2

4

P176

19F

A1

2

≤2

4

1

1

1

0.5

4

>2

2

2

4

P183

19F

A1

2

≤2

>4

1

1

1

0.5

8

>2

1

2

4

P186

19F

A1

2

≤2

4

1

1

1

0.5

8

>2

1

2

4

P192

19F

A1

2

≤2

4

1

1

1

0.5

4

>2

2

2

4

P198

19F

A1

2

≤2

>4

1

1

1

0.5

8

>2

2

2

4

P199

19F

A1

2

≤2

>4

1

1

1

0.5

8

>2

1

2

4

P200

19F

A1

4

≤2

>4

1

1

1

0.5

4

>2

1

2

4

P203

19F

A1

2

≤2

>4

1

1

2

0.5

8

>2

2

2

4

P204

19F

A1

4

≤2

>4

1

1

1

0.5

4

>2

1

2

4

P179

19F

 

4

≤2

>4

1

1

1

0.5

4

>2

1

2

4

P190

19F

 

4

≤2

>4

2

2

2

0.5

4

>2

1

1

>4

P177

6B

B1

4

≤2

>4

1

1

1

0.5

4

>2

1

1

>4

P178

6B

B1

2

≤2

>4

1

1

1

0.5

4

>2

1

2

>4

P180

6B

B1

4

4

>4

1

1

1

0.5

4

>2

1

2

4

P181

6B

B1

4

4

>4

1

1

1

0.5

4

>2

1

1

>4

P185

6B

B1

4

≤2

>4

1

1

1

0.5

4

>2

1

2

>4

P194

6B

B1

2

≤2

>4

1

1

1

0.5

4

>2

1

2

>4

P195

6B

B1

2

≤2

>4

1

1

1

0.5

4

>2

1

2

>4

P201

6B

B1

4

≤2

>4

1

1

1

0.5

4

>2

1

2

>4

P182

6B

 

2

≤2

4

1

0.5

1

≤0.25

4

>2

1

2

>4

P197

6B

 

≤0.03

≤2

≤0.5

≤0.06

≤0.12

≤0.12

≤0.25

4

≤0.25

≤0.5

1

≤0.5

P189

23F

C1

2

≤2

>4

1

1

1

≤0.25

8

>2

1

2

≤0.5

P205

23F

C1

2

≤2

>4

1

1

1

0.5

8

>2

1

2

4

P175

23F

 

4

≤2

>4

2

1

2

0.5

8

>2

1

2

4

P188

23F

 

4

≤2

>4

2

1

2

0.5

8

>2

1

2

4

P196

23F

 

2

≤2

>4

2

1

1

0.5

8

>2

1

2

>4

P191

6A

D1

≤0.03

≤2

≤0.5

≤0.06

≤0.12

≤0.12

≤0.25

4

>2

1

1

4

P202

6A

D1

0.06

≤2

≤0.5

≤0.06

≤0.12

≤0.12

≤0.25

8

>2

1

1

4

P184

9V

 

4

4

>4

2

2

2

0.5

8

>2

2

1

>4

P187

3

 

≤0.03

≤2

≤0.5

≤0.06

≤0.12

≤0.12

≤0.25

4

≤0.25

2

1

≤0.5

  1. a Isolates P151, P154, and P156 were from blood, nasopharynx, and CSF of the meningitis patient, respectively. All other isolates were from nasopharynx of children attending the same kindergarten as the patient.
  2. b PFGE type, Pulse field gel electrophoresis pulsotype; see Figure 1.
  3. c AUG, amoxicillin/clavulanic acid; CHL, chloramphenicol; CRO, ceftriaxone; ERY, erythromycin; FEP, cefepime; FRX, cefuroxime; FTX, cefotaxime; LEV, levofloxacin; LID, Linezolid; MEM, meropenem; PEN, penicillin; SXT, trimethoprim/sulfamethoxazole. All isolates were resistant to tetracycline (MIC > 8 ug/ml) except isolate P187, which was susceptible (MIC ≤ 0.5 ug/ml). All isolates were susceptible to vancomycin (MIC ≤ 0.5 ug/ml).