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Table 1 Anti-LCMV activity of PAP in CBA mice

From: CNS activity of Pokeweed Anti-viral Protein (PAP) in mice infected with Lymphocytic Choriomeningitis Virus (LCMV)

    Disease Unset
    Days after inoculation with LCM Virus
  Survival (days) Weight loss (grams) Decreased mobility Convulsions Hair disheveled
Vehicle      
Mouse #1* <<1 NA 0 NA NA
Mouse #2* <<1 NA 0 NA NA
Mouse #3* <<1 NA 0 NA NA
Mouse #4 6 1.5 4.5 5.5 4.5
Mouse #5 6 2 4.5 5.5 4.5
Mouse #6 7 2 5 6 5
Mouse #7 7 1.5 5 6 5
Mouse #8 7 2.5 5 6 5
Mouse #9 7 4.5 5 6 5
Mouse #10 7 4.5 5 6 5
Mouse #11 7 4.5 5 6 5
Mouse #12 8 2 6 7 6
Mouse #13 8 2.5 6 7 6
Mouse #14 8 1 6 7 6
Mouse #15 8 1.5 6 7 6
Mouse #16 8 2 6 7 6
Mouse #17 8 2 6 7 6
Mouse #18 7 1.5 5 6 5
Mouse #19 8 2 6 7 6
Mouse #20 8 1.5 6 7 6
PAP 0.25 mg/kg      
Mouse #1 <<1 NA NA NA NA
Mouse #2 <<1 NA NA NA NA
Mouse #3 6 1 4.5 5.5 5
Mouse #4 7 1.5 5 6 5
Mouse #5 8 1.5 6 7 5.5
Mouse #6 21 0 10 NO NO
Mouse #7 21 0 10 NO NO
Mouse #8 21 0 10 NO NO
Mouse #9 21 0 10 NO NO
Mouse #10 21 0 10 NO NO
  1. *Mouse died after intracerebral injection; NA = not applicable, NO = not observed