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Table 1 Description of studies included in meta-analysis.

From: A commercial line probe assay for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis

Author (year)

Country

Reference Test

Blinded to reference test?

Sample

Sample size (# resistant / # sensitive)

Sensitivity (95% CI)

Specificity (95% CI)

Ahmad (2002)

Kuwait

BACTEC 460

Not Specified

Isolate

29/12

0.97 (.82–1.0)

1.0 (.74–1.0)

De Oliveira (1998)

Brazil

Proportion

Not Specified

Isolate

113/15

0.97 (.92–.99)

1.0 (.78–1.0)

Gamboa (1998)

Spain

BACTEC 460

Not Specified

Isolate

46/13

1.0 (.92–1.0)

1.0 (.75–1.0)

Hirano (1999)

Japan

Proportion

Not Specified

Isolate

90/26

0.92 (.85–.97)

1.0 (.87–1.0)

Johansen (2003)

Denmark

BACTEC 460

Not Specified

Isolate

35/24

0.97 (.85–1.0)

1.0 (.86–1.0)

Jureen (2004)

Sweden

BACTEC 460

Not Specified

Isolate

27/26

1.0 (.87–1.0)

0.92 (.75–.99)

Lemus (2004)

Belgium

BACTEC 460, Proportion

Yes

Isolate

10/10

1.0 (.69–1.0)

1.0 (.69–1.0)

Rossau (1997)

Belgium

Proportion

Not Specified

Isolate

203/61

0.98 (.95–.1.0)

1.0 (.94–1.0)

Sintchenko (1999)

Australia

BACTEC 460

Not Specified

Isolate

22/11

0.96 (.77–1.0)

1.0 (.72–1.0)

Somoskovi (2003)

USA

Proportion

Not Specified

Isolate

64/37

0.95 (.87–.99)

1.0 (.91–1.0)

Srivastava (2004)

India

MIC

Not Specified

Isolate

45/10

0.82 (.68–.92)

1.0 (.69–1.0)

Tracevska (2002)

Latvia

BACTEC 460

Not Specified

Isolate

34/19

1.0 (.90–1.0)

1.0 (.82–1.0)

Traore (2000)

Belgium

Proportion

Not Specified

Isolate

266/145

0.99 (.96–1.0)

1.0 (.98–1.0)

Watterson (1998)

England

BACTEC 460, Proportion

Not Specified

Isolate

16/16

1.0 (.80–1.0)

0.94 (.70–1.0)

De Beenhouwer (1995)

Belgium

Proportion

Not Specified

Clinical Specimen

21/46

0.91 (.70–1.0)

1.0 (.92–1.0)

Gamboa (1998)

Spain

BACTEC 460

Not Specified

Clinical Specimen

46/13

0.98 (.89–1.0)

1.0 (.75–1.0)

Johansen (2003)

Denmark

BACTEC 460

Not Specified

Clinical Specimen

26/21

1.0 (.87–1.0)

1.0 (.84–1.0)

Watterson (1998)

England

BACTEC 460, proportion

Yes

Clinical Specimen

10/24

0.80 (.44–.98)

1.0 (.86–1.0)