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Table 3 Sensitivity and specificity of phage assays in studies that reported results stratified by smear microscopy status

From: Bacteriophage- based tests for the detection of Mycobacterium tuberculosis in clinical specimens: a systematic review and meta- analysis

   

Sputum smear microscopy status

   

Smear positive

Smear negative

Study

Country

Number of Specimens (culture positive)

Sensitivity

Specificity

Sensitivity

Specificity

Albert (2002)

South Africa

1618 (207)

0.87 (0.79,0.92)

0.83 (0.69,0.93)

0.49 (0.37,0.60)

0.99 (0.99,1.00)

Alcaide (2003)

Spain

2048 (144)

0.75 (0.66,0.83)

0.76 (0.55,0.91)

0.13 (0.04,0.27)

0.99 (0.99,1.00)

Bellen (2003)

Philippines

206 (103)

0.29 (0.20, 0.40)

0.83 (0.67,0.93)

0.45 (0.17,0.77)

0.89 (0.78,0.95)

Butt (2004)

Pakistan

160 (60)

0.76 (0.60, 0.88)

0.60 (0.15,0.95)

0.78 (0.52,0.93)

0.98 (0.93,1.00)

Muzaffar (2002)

Pakistan

514 (245)

0.87 (0.82,0.92)

0.88 (0.63,0.98)

0.67 (0.55,0.78)

0.98 (0,96,1.00)