Table 4 Bacteriologic and clinical outcome in per-protocol bacteriologically evaluable patients with S pneumoniae isolates resistant to penicillin G (Pen G) and/or erythromycin A (Ery A).
|  |  | MIC Susceptibility* (μg/mL) |  |  | ||
|---|---|---|---|---|---|---|
Subject No. | Isolate (Source) | TEL | Pen G | Ery A | Bacteriologic Outcome†| Clinical Outcome |
Subjects with single-pathogen S pneumoniae isolate | ||||||
1 | S pneumoniae (sputum) | 0.030 (S) | 0.030 (S) | b>8.000 (R) | Eradication | Cure |
2 | S pneumoniae (sputum) | 0.030 (S) | 2.000 (R) | 0.250 (S) | Presumed eradication | Cure |
3 | S pneumoniae (sputum) | 0.500 (S) | 2.000 (R) | 8.000 (R) | Presumed eradication | Cure |
Subjects with multiple-pathogen S pneumoniae isolate | ||||||
4 | S pneumoniae (sputum) | 0.060 (S) | 2.000 (R) | 4.000 (R) | Presumed eradication | Cure |
| Â | M catarrhalis | 0.120 (S) | ND | 0.120 | Presumed eradication | Cure |
5 | S pneumoniae (sputum) | 0.250 (S) | 2.000 (R) | 8.000 (R) | Presumed eradication | Cure |
6 | S pneumoniae (sputum) | 0.030 (S) | 2.000 (R) | 0.060 (S) | Presumed eradication | Cure |
| Â | H influenzae | 0.002 (S) | ND | 1.000 | Presumed eradication | Cure |
| Â | M catarrhalis | 0.120 (S) | ND | 0.250 | Presumed eradication | Cure |
7 | S pneumoniae (sputum) | 0.500 (S) | 2.000 (R) | 8.000 (R) | Presumed eradication | Cure |
| Â | H influenzae | 2.000 (S) | ND | 4.000 | Presumed eradication | Cure |
8 | S pneumoniae (blood) | 1.000 (S) | 0.250 (I) | 8.000 (R) | Presumed eradication | Cure |
| Â | H influenzae | 1.000 (S) | ND | 4.000 | Presumed eradication | Cure |
9 | S pneumoniae (blood) | 1.000 (S) | 0.500 (I) | 8.000 (R) | Presumed eradication | Cure |
| Â | H influenzae | 8.000 (R) | ND | 4.000 | Presumed eradication | Cure |
| Â | S aureus | 0.120 (S) | ND | 0.500 | Presumed eradication | Cure |