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Table 3 Haematological and biochemical findings in a study of 60 patients with blood culture-proven typhoid fever

From: Clinical outcomes in typhoid fever: adverse impact of infection with nalidixic acid-resistant Salmonella typhi

Variable

Frequency, overall (n = 60)

NARST (n = 47)

NASST (n = 13)

MDR-ST (n = 22)

NonMDR-ST (n = 38)

Anaemia *

19 (32)

15 (32)

4 (31)

6 (27)

13 (34)

Leucopenia *

10 (17)

8 (17)

2 (15)

4 (18)

6 (16)

Leucocytosis *

6 (10)

5 (11)

1 (8)

2 (9)

4 (11)

Thrombocytopenia *

8 (13)

6 (13)

2 (15)

3 (14)

5 (13)

AST > 2 × ULN

27 (45)

23 (49)

4 (31)

9 (41)

18 (47)

AST > 5 × ULN

8 (13)

8 (17)

--

3 (14)

5 (13)

ALT > 2 × ULN

18 (30)

16 (34)

2 (15)

6 (27)

12 (32)

ALT > 5 × ULN

4 (7)

4 (9)

--

1 (5)

3 (8)

  1. NARST = nalidixic acid-resistant Salmonella typhi
  2. NASST = nalidixic acid-sensitive Salmonella typhi
  3. MDR-ST = multidrug-resistant Salmonella typhi
  4. AST = alanine aminotransferase
  5. ALT = aspartate aminotransferase
  6. ULN = upper limit of normal
  7. MIC = minimum inhibitory concentration
  8. -- no patients in this category
  9. * defined by cut-off values as given in the text
  10. All data presented as number (%) of patients