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Table 6 Mean liver histological scores before and after interferon-alpha treatment in 51 Taiwanese chronic hepatitis C patients

From: High versus standard doses interferon-alpha in the treatment of naïve chronic hepatitis C patients in Taiwan: a 10-year cohort study

 

Before treatment

Follow-up†

P value‡

Periportal inflammation

1.25 ± 1.47

0.84 ± 1.27

0.0419

Intralobular necrosis

1.02 ± 1.24

0.49 ± 0.92

0.0129

Portal inflammation

1.88 ± 1.24

1.16 ± 1.32

0.0030

Total necroinflammatory score

4.08 ± 2.86

2.51 ± 3.06

0.0037

Fibrosis

1.12 ± 1.09

1.10 ± 1.22

0.8485

  1. † Mean follow-up time was 1.9 year (range 0.5–5.5 years) after end of treatment.
  2. ‡ Wilcoxon's signed rank test.