|
Maternal variables in pregnancy
|
Mothers during pregnancy n = 90
|
Infants at one year of age n = 57
|
|---|
| |
Proportion (%) with "high IFN-γ" (> mediana)
|
P value
|
Proportion (%) with "high IFN-γ" (> mediana)
|
P value
|
|---|
|
Helminths
| | | | |
|
none
|
12/19 (63%)
| |
4/17 (24%)
| |
|
hookworm
|
11/36 (31%)
|
0.025
|
16/20 (80%)
|
0.001
|
|
S. mansoni
|
12/22 (55%)
|
0.75
|
7/12 (58%)
|
0.12
|
|
HIV infection
| | | | |
|
Negative
|
39/78 (50%)
| |
26/49 (53%)
| |
|
positive
|
5/12 (42%)
|
0.76
|
3/8 (38%)
|
0.47
|
|
Malaria parasitaemia
| | | | |
|
Negative
|
41/77 (53%)
| |
25/49 (51%)
| |
|
Positive
|
3/13 (23%)
|
0.07
|
4/8 (50%)
|
1.00
|
|
Age
| | | | |
|
< 25 years
|
28/61 (46%)
| |
19/37 (51%)
| |
|
25 or older
|
16/29 (55%)
|
0.50
|
10/20 (50%)
|
1.00
|
|
Education (1 mv)
| | | | |
|
none/ primary
|
29/55 (53%)
| |
19/34 (56%)
| |
|
secondary/ tertiary
|
15/34 (44%)
|
0.52
|
10/23 (43%)
|
0.42
|
|
BCG scar (3 mv)
| | | | |
|
absent
|
11/28 (39%)
| |
10/14 (71%)
| |
|
present
|
32/59 (54%)
|
0.25
|
18/41 (44%)
|
0.12
|
-
a The median level of IFN-γ production in response to CFP for mothers was 69 pg/ml; for infants 206 pg/ml. mv: missing values
