TY - JOUR AU - Eisinger, Dirk AU - Thulke, Hans-Hermann AU - Selhorst, Thomas AU - Müller, Thomas PY - 2005 DA - 2005/03/07 TI - Emergency vaccination of rabies under limited resources – combating or containing? JO - BMC Infectious Diseases SP - 10 VL - 5 IS - 1 AB - Rabies is the most important viral zoonosis from a global perspective. Worldwide efforts to combat the disease by oral vaccination of reservoirs have managed to eradicate wildlife rabies in large areas of central Europe and North-America. Thus, repeated vaccination has been discontinued recently on a geographical scale. However, as rabies has not yet been eradicated globally, a serious risk of re-introduction remains. What is the best spatial design for an emergency vaccination program – particularly if resources are limited? Either, we treat a circular area around the detected case and run the risk of infected hosts leaving the limited control area, because a sufficient immunisation level has not yet been built up. Or, initially concentrate the SAME resources in order to establish a protective ring which is more distant from the infected local area, and which then holds out against the challenge of the approaching epidemic. SN - 1471-2334 UR - https://doi.org/10.1186/1471-2334-5-10 DO - 10.1186/1471-2334-5-10 ID - Eisinger2005 ER -