Skip to main content

Table 4 Deposition of PrPSc in microdissected areas of ME7 scrapie model

From: Microdissection: A method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesis

DPI

A

B

C

 

D

E

F

G

 

W

I

W

I

W

I

W

I

W

I

W

I

W

I

30

              

60

      

+

+

 

+

 

+

 

+

90

  

?

 

+

+

+

+

?

+

+

+

+

+

120

+

N/A

?

+

+

+

+

+

+

+

+

+

+

+

150

+

N/A

+

+

+

+

+

+

+

+

+

+

+

+

EP

+

N/A

+

+

+

+

+

+

+

+

+

+

+

+

  1. Comparison of dissected brain areas (A-G as in Fig. 2) throughout time course of disease (dpi) in ME7 scrapie model. PrPSc deposition (+) visualized by immunocytochemistry (I) and western blotting (W)using 6H4Mab, (?) denotes where PrPSc was visualized in one brain only(see section 2.4), (N/A) section not available.