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Table 3 Deposition of PrPSc in microdissected areas of 87V scrapie model.

From: Microdissection: A method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesis

DPI

A

B

C

D

E

F

G

 

W

I

W

I

W

I

W

I

W

I

W

I

W

I

30

              

60

              

90

              

120

              

150

   

+

?

+

        

180

  

+

N/A

+

N/A

     

N/A

  

210

  

+

+

+

+

     

N/A

  

240

  

+

+

+

+

+

+

?

+

+

+

?

+

270

 

+

+

+

+

+

+

+

?

+

+

+

+

+

300

All -ve

+

+

+

+

+

+

+

?

+

+

+

+

+

  1. Comparison of dissected brain areas (A-G as in Fig. 2) throughout time course of disease (dpi) in 87V scrapie model. PrPSc deposition (+) visualised by immunocytochemistry (I) and western blotting(W) using 6H4Mab, (?) denotes where PrPSc was visualised in one brain only(see section 2.4), section not available (N/A).