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Table 1 Demographic, clinical and laboratory details of 14 patients with GAS necrotising fasciitis

From: Streptococcal necrotising fasciitis from diverse strains of Streptococcus pyogenes in tropical northern Australia: case series and comparison with the literature

No Age/Gender/Aboriginal/Year Co-morbidities Prior lesions Systolic BP at presenttion (mmHg) Creatinine (μmol/L) (NR 50–100) Blood culture emmST a STSSb
1 45/F/Y/2001 Alcohol excess Right knee abrasion 85 810 Neg new emmST Y
2 50/F/Y/1994 Rheumatoid arthritis Nil 100 352 Pos emm56 N
3 47/F/Y/2000 Hemodialysis, Hypertension Nil 85 739 Pos emmST3757 Y
4 38/F/Y/2001 Type 2 diabetes, Hemodialysis, Cryptococcal pneumonitis Buttock ulcer 60 408 Pos no sequence Y
5 61/M/N/2001 Rheumatoid arthritis, Corticosteroid therapy, Splenectomy Vasculitic leg ulcer 70 249 Pos emm3.2 Y
6 60/M/N/2001 Rheumatoid arthritis, Methotrexate therapy, Pulmonary fibrosis Leg ulcer 90 237 Neg emm70 Y
7 27/M/N/1996 Alcohol excess Nil 70 172 Neg emm58 Y
8 34/F/Y/1996 SLE, Anti-Phospholipid syndrome, Corticosteroids, Renal impairment Left thigh skin sore 100 329 Pos emm69 N
9 44/M/Y/2000 Type 2 diabetes, Alcohol excess, Renal impairment Wound from catfish barb 90 271 Neg emm49.3 Y
10 27/F/N/1999 Nil Nil 90 77 Neg emm104 N
11 32/F/N/1999 Nil Buttock excoriation post-cycling 100 177 Neg emm1 N
12 59/F/N/1999 Nil Nil 90 118 Neg emm22 Y
13 50/M/Y/1997 Alcohol excess, Cirrhosis Leg ulceration 100 112 Pos emm4 N
14 61/M/N/2001 Alcohol excess, Hypertension, Gout Ulcerated gouty tophus 90 659 Pos emm3 Y
No WCC/Lymph c (×10 9 /L) Albumin (g/L) (NR 35–45) Infection site Time to surgery after presentation Operation performed Antibiotic therapy Myo-necrosis Died
1 5.7/0.2 21 Right leg 4 days Debridement, Fasciotomy Meropenem, Clindamycin Yes Yes
2 5.2/0.5 22 Right arm 6 days Fasciotomy Penicillin Yes Yes
3 9.6/0.3 33 Right breast/Chest wall 5 days Debridement Penicillin No Yes
4 9.3/0.4 34 Left leg/Abdominal wall 2 days Debridement Penicillin, Clindamycin No Yes
5 36.7/0.7 23 Left leg 1 day Above knee amputation Meropenem, Tobramycin, Clindamycin No No
6 23.7/0.5 29 Right leg 0 days Below knee amputation Cefazolin, Clindamycin No No
7 5.2/0.1 25 Right leg 5 days Debridement Penicillin, Clindamycin No No
8 7.0/0.3 33 Left leg/Abdominal wall 7 days Debridement Penicillin, Clindamycin Yes No
9 22.8/0.8 11 Right foot 2 days Above knee amputation Flucloxacillin, Metronidazole, Gentamicin Yes No
10 23.3/1.0 29 Left shoulder/Chest wall 6 days Debridement Meropenem, Clindamycin No No
11 21.8/0.5 17 Right leg/Buttock/Perineum 2 days Debridement Penicillin, Clindamycin No No
12 4.8/0.4 18 Left leg/Abdominal wall 2 days Debridement Penicillin, Clindamycin No No
13 10.5/0.7 21 Left leg 5 days Debridement Penicillin, Clindamycin No No
14 4.0/0.2 28 Right leg 4 days Above knee amputation Penicillin, Clindamycin No No
  1. a Emm sequence type (see methods for details)
  2. b Streptococcal toxic shock syndrome (see methods for details)
  3. c WCC-total blood white cell count (normal range <11.0 × 109/L) Lymph-blood lymphocyte count
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