Skip to main content

Advertisement

Table I Characteristics and immune parameters of patient groups and controls

From: Zinc/copper imbalance reflects immune dysfunction in human leishmaniasis: an ex vivo and in vitro study

Group (n) Age Male/Female Anti-LeishmaniaIgG (O.D.) Lympho-proliferation (cpm)b IFN-γ (pg/ml)b
Urban controls (10) 24.9 (2.0) 7/3 < cut-off < 100 < 20
Endemic controls (15) 28.7 (8.8) 3/12 < cut-offa ND < 20
LCL0 (14) 28.4 (12.7) 10/4 0.178 (0.073) 2737 (1178) 612 (207)
LCL3 (7) 28.5 (11.2) 5/2 0.074 (0.021) ND 685 (348)
ML (7) 44.4 (11.9) 5/2 0.016 (0.005) > 5000 > 2000
VL (10) 18.4 (3.8) 6/4 0.188 (0.072) < 100 < 20
  1. Results are expressed as mean (SEM). ND: not done. LCL0 and LCL3, localized cutaneous leishmaniasis at 0 and 3 months of treatment, ML mucosal leishmaniasis, VL visceral leishmaniasis.
  2. a One endemic control displayed positive serology and was discarded from analysis.
  3. b Following stimulation of tenfold diluted whole blood with live Leishmania promastigotes.