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Table I Characteristics and immune parameters of patient groups and controls

From: Zinc/copper imbalance reflects immune dysfunction in human leishmaniasis: an ex vivo and in vitro study

Group (n)

Age

Male/Female

Anti-LeishmaniaIgG (O.D.)

Lympho-proliferation (cpm)b

IFN-γ (pg/ml)b

Urban controls (10)

24.9 (2.0)

7/3

< cut-off

< 100

< 20

Endemic controls (15)

28.7 (8.8)

3/12

< cut-offa

ND

< 20

LCL0 (14)

28.4 (12.7)

10/4

0.178 (0.073)

2737 (1178)

612 (207)

LCL3 (7)

28.5 (11.2)

5/2

0.074 (0.021)

ND

685 (348)

ML (7)

44.4 (11.9)

5/2

0.016 (0.005)

> 5000

> 2000

VL (10)

18.4 (3.8)

6/4

0.188 (0.072)

< 100

< 20

  1. Results are expressed as mean (SEM). ND: not done. LCL0 and LCL3, localized cutaneous leishmaniasis at 0 and 3 months of treatment, ML mucosal leishmaniasis, VL visceral leishmaniasis.
  2. a One endemic control displayed positive serology and was discarded from analysis.
  3. b Following stimulation of tenfold diluted whole blood with live Leishmania promastigotes.
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BMC Infectious Diseases

ISSN: 1471-2334

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