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Table 1 Inhibitory activity of PJ-S21 on infection by primary HIV-1 strains

From: Punica granatum(Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide

Primary strain Subtype, Coreceptor use ED50* mg/ml ED90* mg/ml
92RW008 A, R5 0.50 ± 0.05 2.76 ± 0.28
94UG103 A, X4R5 1.42 ± 0.54 3.42 ± 0.98
92US657 B, R5 0.62 ± 0.11 2.86 ± 0.33
93IN101 C, R5 3.56 ± 1.10 8.87 ± 2.55
93MW959 C, R5 1.02 ± 0.19 3.54 ± 0.90
92UG001 D, X4R5 0.62 ± 0.17 2.94 ± 0.85
93THA051 E, X4R5 0.86 ± 0.01 4.09 ± 0.08
93BR020 F, X4R5 4.25 ± 0.78 8.31 ± 1.04
RU570 G, R5 0.42 ± 0.09 1.54 ± 0.16
BCF02 Group O, R5 0.59 ± 0.29 3.92 ± 0.27
  1. * ED50(90) = effective dose(s) of PJ-S21 for 50% (90%) inhibition of infection. One gram of PJ-S21 contains approximately 3.2 mg of the inhibitors adsorbed to starch from pomegranate juice.