Expression of TLR9 in response to SARS-CoV infection. A. Expression range (log2) for TLR9, TLR2 and TLR4. The expression range for TLR9 was greater than expected (* represents a P-value for TLR9 of 0.016). B. Comparison of the CpG motif (GTCGTT) copy number in coronaviruses and other viruses linked to respiratory diseases. Accession numbers are as follows: SARS coronavirus SIN2500 – AY283794, Human coronavirus 229E – NC_002645, Murine hepatitis virus – NC_001846, Avian infectious bronchitis virus – NC_001451, Bovine coronavirus – NC_003045, Human rhinovirus B – NC_001490, Human parainfluenza virus 1 – NC_003461, Human respiratory syncytial virus – NC_001781, Human metapneumovirus – NC_004148.