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Table 1 Characteristics of patients who received intrapleural streptokinase (IPSTK group, n = 12) and those who did not (Non IPSTK group, n = 19)

From: A study of empyema thoracis and role of intrapleural streptokinase in its management

Parameters IPSTK group (n = 12) Non IPSTK group (n = 19) P value
Age (years) 40 ± 15 41 ± 17 0.87
Sex (male/female) 9/3 16/3 0.53
Duration of symptoms (months)* 2.0 (0.2–12) 1.5 (0.1–36) 0.49
Chronic Empyema† 9 (75%) 11 (57.9%) 0.32
Hemoglobin (gm/dL) 10.1 ± 2.6 9.6 ± 2.0 0.63
TLC (/cmm) 11,100 ± 5489 14,494 ± 8271 0.19
ESR (1st hr) 46 ± 19 57 ± 24 0.17
Blood Urea (mg/dL) 36 ± 15 41 ± 21 0.08
Serum creatinine (mg/dL) 1.2 ± 0.5 1.3 ± 0.8 0.64
Serum sodium (meq/L) 135.7 ± 4.1 134.9 ± 7.3 0.69
Serum potassium (meq/L) 4.3 ± 0.8 4.1 ± 0.4 0.38
Total bilirubin (mg/dL) 0.6 ± 0.3 0.8 ± 0.5 0.06
AST (IU/L)* 28 (17–218) 32 (12–381) 0.48
ALT (IU/L)* 19 (10–295) 33 (10–461) 0.54
SAP (IU/L) 203 ± 110 200 ± 105 0.95
Serum albumin (gm%) 2.9 ± 0.7 3.1 ± 0.7 0.54
Pl F total cells (/cmm)* 5000 (500–90,000) 2500 (800–160,000) 0.25
Pl F neutrophil count (/cmm)* 4500 (500–85,000) 2000 (100–150,000) 0.21
Pl F protein (gm/dL) 4.9 ± 1.1 4.4 ± 1.8 0.29
Pl F glucose (mg/dL)* 32 (0–80) 12 (3–70) 0.17
Presence of loss of lung volume 8 (66.7%) 12 (63.2%) 0.84
Tubercular empyema 6 (50%) 7 (36.8%) 0.47
  1. TLC: Total leukocyte count, ESR: Erythrocyte sedimentation rate, AST: Aspartate aminotransferase, ALT: Alanine aminotransferase, SAP: Serum alkaline phosphatase, Pl F: Pleural fluid. Data is presented as mean ± standard deviation except those variables marked by a * where data is presented as median with range. †Patients with duration of symptoms more than 4 weeks were designated as having chronic empyema