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Table 1 Clinical characteristics and comparison of the Ofloxacin & Rifampicin and Doxycycline & Rifampicin group

From: Ofloxacin plus Rifampicin versus Doxycycline plus Rifampicin in the treatment of brucellosis: a randomized clinical trial [ISRCTN11871179]

Clinical findings Doxycycline & Rifampicin group (n = 14) Ofloxacin & Rifampicin group (n = 15)
Age (years) (median-range) 29 (24–61) 35 (18–60)
Male/Female 11/3 13/2
Hepatomegaly (n) 7 9
Fever (n) 13 15
Arthralgia (n) 13 13
Headache (n) 10 11
Sweating (n) 12 10
Splenomegaly (n) 7 7
Diagnosis with culture (n) 4 3
Diagnosis with agglutination (n) 12 13
Adverse effects   
- Diarrhea (n) 1 2
- Nausea and vomiting (n) 3 1
Complication (n) 2 Sacroileitis 1 Sacroileitis **
1 Orchitis
Relapse (n) 2 2 **
Duration of fever after starting treatment (mean ± SD) (hours) 106 ± 26 74 ± 30 *
  1. *p < 0.05. ** p > 0.05