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Table 3 Effects of various inhibitors on S. marcescens W225 invasion of RT112 epithelial cells

From: Serratia marcescens internalization and replication in human bladder epithelial cells

Inhibitor concentration [%] invasion MOI 2 [%] cytotoxicity MOI 2 [%] invasion MOI 10 [%] cytotoxicity MOI 10
None - 100 16.0 ± 2.4 100 90.0 ± 1.8
Chloroquine 200 μg/ml 98.0 ± 4.1 19.0 ± 1.8 97.2 ± 3.7 100
Cycloheximide 10 μg/ml 100 15.3 ± 2.6 102 ± 4.4 100
Cytochalasin D 5 μg/ml 54.0 ± 2.3 21.3 ± 2.6 62.0 ± 3.1 100
Dansylcadaverine 500 μM 100 18.2 ± 1.8 100 92.3 ± 5.4
Wortmannin 25 μM 55.0 ± 2.8 48.0 ± 4.4 3.0 ± 0.5 100
Colchizine 0.2 μg/ml 23.0 ± 2.1 7.2 ± 1.3 58.4 ± 6.3 46.8 ± 5.3
Paclitaxel 1 μg/ml 21.5 ± 3.2 11.7 ± 6.3 44.4 ± 5.8 40 ± 2.2