Table 2 Measurements of the effect of 100 mM NaCl on the inhibition of the growth of otitis media pathogens by human lysozyme (hLz), lactoferrin (hLf), β defensin-1 (HBD-1) and β defensin-2 (HBD-2), using the radial inhibition assay.

Molecule

Total amount of protein/peptide added (in a total volume of 4 μl)

NTHi

M. catarrhalis

S. pneumoniae 3

S. pneumoniae 6B

hLz

4 μg

-

-

-

-

10 μg

-

-

-

-

40 μg

-

-

-

-

hLf

4 μg

-

-

-

-

10 μg

-

-

-

-

40 μg

-

-

-

-

HBD-1

4 μg

-

-

-

-

10 μg

-

-

-

-

40 μg

ND

ND

ND

ND

HBD-2

4 μg

8.8 ± 1.0 (C)

9.0 ± 0.7 (C)

-

-

10 μg

11.3 ± 0.3 (C)

11.0 ± 0.7 (C)

40 μg

ND

ND

ND

ND