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Table 2 Measurements of the effect of 100 mM NaCl on the inhibition of the growth of otitis media pathogens by human lysozyme (hLz), lactoferrin (hLf), β defensin-1 (HBD-1) and β defensin-2 (HBD-2), using the radial inhibition assay.

From: Antimicrobial activity of innate immune molecules against Streptococcus pneumoniae, Moraxella catarrhalis and nontypeable Haemophilus influenzae

   Bacteria
Molecule Total amount of protein/peptide added (in a total volume of 4 μl) NTHi M. catarrhalis S. pneumoniae 3 S. pneumoniae 6B
hLz 4 μg - - - -
  10 μg - - - -
  40 μg - - - -
hLf 4 μg - - - -
  10 μg - - - -
  40 μg - - - -
HBD-1 4 μg - - - -
  10 μg - - - -
  40 μg ND ND ND ND
HBD-2 4 μg 8.8 ± 1.0 (C) 9.0 ± 0.7 (C) - -
  10 μg 11.3 ± 0.3 (C) 11.0 ± 0.7 (C)   
  40 μg ND ND ND ND
  1. Diameter (mm) of the inhibition zone (average of 3 separate experiments ± SD) caused by the different concentrations of the antimicrobial molecules is given in the column below each pathogen. -: No effect; ND: Not done