Table 1 Measurements of the effect of human lysozyme (hLz), lactoferrin (hLf), β defensin-1 (HBD-1) and β defensin-2 (HBD-2) on the growth of otitis media pathogens, using the radial inhibition assay.

hLz

50 μg

-

4.6 ± 0.4 (P)

6.2 ± 0.7 (C)

6.7 ± 0.9 (C)

100 μg

-

5.6 ± 0.7 (P)

7.2 ± 0.5 (C)

7.4 ± 0.6 (C)

200 μg

-

6.2 ± 0.5 (P)

7.7 ± 0.6 (C)

8.2 ± 0.7 (C)

hLf

4 μg

-

-

-

-

10 μg

E

-

E

-

40 μg

E

E

E

E

HBD-1

4 μg

-

-

-

-

10 μg

-

7.7 ± 0.6 (P)

-

-

40 μg

ND

ND

ND

ND

HBD-2

4 μg

9.7 ± 2.5 (C)

11.7 ± 0.6 (C)

8.7 ± 1.5 (C)

8.7 ± 1.2 (C)

10 μg

12.3 ± 2.9 (C)

14.7 ± 0.6 (C)

10 ± 1.3 (C)

10.7 ± 1.5 (C)

40 μg

ND

ND

ND

ND