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Table 3 Effects of tetrapyrroles on cell viability and growth.

From: Prevention of poxvirus infection by tetrapyrroles

Compound

CC50 (µg/mL)

 

Cytostatic activitya

Cell proliferationb

ZnPPIX

370

25

CuPcS(3444)

> 1000

> 500

TNapPS

400

 

TAnthPS

350

120

TPP[2,6-(OH)2]

90

20

CuHPIX

 

36

Co(III)TPP(2,6-F2)S

300

< 5

  1. aCV-1 cells were seeded at 3.5 × 103 cells/well and allowed to attach overnight, then the compounds (in growth medium) added. Following 24 h incubation, the cells were counted. bThese results were obtained by measuring 3H-thymidine uptake using HeLa S3 cells.