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Table 2 HRHPV Hybrid Capture II performance for the diagnosis of CIN2/3

From: Evaluation of adjunctive HPV testing by Hybrid Capture II®in women with minor cytological abnormalities for the diagnosis of CIN2/3 and cost comparison with colposcopy

referral smear cut off n sensitivity specificity NPV NLR OR
MD & BL 1 RLU 133 97% 37% 97% 0.089 17
MD & BL 3 RLU 133 97% 46% 98% 0.072 26
1xMD 1 RLU 110 97% 36% 97% 0.096 17
1xMD 3 RLU 110 97% 41% 97% 0.083 19
3xBL 1 RLU 23 100% 52% 100% NA NA
3xBL 3 RLU 23 100% 64% 100% NA NA
MD & BL in woman >30y 1 RLU 66 100% 47% 100% NA NA
MD & BL in woman >30y 3 RLU 66 100% 58% 100% NA NA
  1. MD = mild dyskaryosis, BL= borderline, NA = non applicable due to 0 in 2 × 2 table