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Table 5 Factors related to sexual exposures and reproduction in relation to high anti-HHV-8 antibody titers

From: Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study

  high titer/total pos (%)¥ aOR * 95%CI
Number of lifetime husbands/wives   
0–1§ 247/633 (39.0) 1.0
≥ 2 20/45 (44.4) 1.26 (0.68–2.35)
Test for Trend   χ2 = 0.55, p = 0.46
Marital status   
Single§ 51/175 (29.1) 1.0
Married 166/458 (36.2) 1.11 (0.73–1.69)
Widowed 75/162 (46.3) 1.54 (0.92–2.59)
Separated/Divorced 31/57 (54.4) 2.44 (1.30–4.58)
Test of Homogeneity (3 df)   χ2 = 10.6, p = 0.01
Number of lifetime sexual partners   
0–2§ 64/166 (38.6) 1.0
3–4 156/423 (36.9) 0.94 (0.65–1.38)
≥ 5 79/202 (39.1) 1.11 (0.71–1.74)
Test for Trend   χ2 = 0.37, p = 0.54
Pregnant (in lifetime)   
Yes§ 189/501 (37.7) 1.0
No 8/17 (47.1) 1.65 (0.61–4.49)
Test of Homogeneity   χ2 = 0.95, p = 0.33
Times pregnant (in lifetime)   
1§ 11/39 (28.2) 1.0
2–3 57/149 (38.3) 1.69 (0.77–3.69)
4–5 54/142 (38.0) 1.50 (0.68–3.29)
≥ 6 68/173 (39.3) 1.45 (0.67–3.15)
Test for Trend   χ2 = 0.03, p = 0.87
Times miscarriage (in lifetime)   
0§ 6/12 (50.0) 1.0
1 37/107 (34.6) 0.56 (0.17–1.89)
≥ 2 39/100 (39.0) 0.61 (0.18–2.06)
Test for Trend   χ2 = 0.10, p = 0.73
Parity   
0–2§ 53/140 (37.9) 1.0
3–4 57/174 (32.8) 0.73 (0.45–1.18)
≥ 5 74/176 (42.1) 0.99 (0.62–1.59)
Test for Trend   χ2 = 0.00, p = 0.95
Number of children (born alive) (for men)   
0–1§ 10/26 (38.5) 1.0
2–3 29/82 (35.4) 0.80 (0.31–2.06)
4–5 31/80 (38.8) 0.76 (0.29–2.01)
≥ 6 49/126 (38.9) 0.69 (0.26–1.79)
Test for Trend   χ2 = 0.50, p = 0.48
Number of mothers and fathers (children)   
1§ 237/608 (39.0) 1.0
≥ 2 67/197 (34.0) 0.82 (0.58–1.16)
Test for Trend   χ2 = 1.30, p = 0.25
Age when periods began   
10–13§ 17/39 (43.6) 1.0
14 34/81 (42.0) 0.93 (0.42–2.04)
15 53/166 (31.9) 0.55 (0.27–1.14)
≥ 16 91/227 (40.1) 0.77 (0.38–1.56)
Test for Trend   χ2 = 0.46, p = 0.50
Age when periods ended   
≤ 45§ 32/94 (34.0) 1.0
46–49 40/100 (40.0) 1.11(0.60–2.08)
≥ 50 85/198 (42.9) 1.24 (0.69–2.23)
Test for Trend   χ2 = 0.74, p = 0.39
Oral contraceptives   
No§ 168/424 (39.6) 1.0
Yes 25/86 (29.1) 0.69 (0.40–1.17)
Test of Homogeneity   χ2 = 1.88, p = 0.17
Injectable contraceptives   
No§ 165/425 (38.8) 1.0
Yes 28/87 (32.2) 0.93 (0.55–1.59)
Test of Homogeneity   χ2 = 0.07, p = 0.80
  1. * Adjusted for age category < 35, 35–44, 45–54, 55–64, or ≥ 65 sex. ¥ Data were not available for all patients for all variables. § These patients served as the reference group. All values were calculated with the χ2 test with 1 df unless noted otherwise.