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Table 5 Factors related to sexual exposures and reproduction in relation to high anti-HHV-8 antibody titers

From: Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study

 

high titer/total pos (%)¥

aOR * 95%CI

Number of lifetime husbands/wives

  

0–1§

247/633 (39.0)

1.0

≥ 2

20/45 (44.4)

1.26 (0.68–2.35)

Test for Trend

 

χ2 = 0.55, p = 0.46

Marital status

  

Single§

51/175 (29.1)

1.0

Married

166/458 (36.2)

1.11 (0.73–1.69)

Widowed

75/162 (46.3)

1.54 (0.92–2.59)

Separated/Divorced

31/57 (54.4)

2.44 (1.30–4.58)

Test of Homogeneity (3 df)

 

χ2 = 10.6, p = 0.01

Number of lifetime sexual partners

  

0–2§

64/166 (38.6)

1.0

3–4

156/423 (36.9)

0.94 (0.65–1.38)

≥ 5

79/202 (39.1)

1.11 (0.71–1.74)

Test for Trend

 

χ2 = 0.37, p = 0.54

Pregnant (in lifetime)

  

Yes§

189/501 (37.7)

1.0

No

8/17 (47.1)

1.65 (0.61–4.49)

Test of Homogeneity

 

χ2 = 0.95, p = 0.33

Times pregnant (in lifetime)

  

1§

11/39 (28.2)

1.0

2–3

57/149 (38.3)

1.69 (0.77–3.69)

4–5

54/142 (38.0)

1.50 (0.68–3.29)

≥ 6

68/173 (39.3)

1.45 (0.67–3.15)

Test for Trend

 

χ2 = 0.03, p = 0.87

Times miscarriage (in lifetime)

  

0§

6/12 (50.0)

1.0

1

37/107 (34.6)

0.56 (0.17–1.89)

≥ 2

39/100 (39.0)

0.61 (0.18–2.06)

Test for Trend

 

χ2 = 0.10, p = 0.73

Parity

  

0–2§

53/140 (37.9)

1.0

3–4

57/174 (32.8)

0.73 (0.45–1.18)

≥ 5

74/176 (42.1)

0.99 (0.62–1.59)

Test for Trend

 

χ2 = 0.00, p = 0.95

Number of children (born alive) (for men)

  

0–1§

10/26 (38.5)

1.0

2–3

29/82 (35.4)

0.80 (0.31–2.06)

4–5

31/80 (38.8)

0.76 (0.29–2.01)

≥ 6

49/126 (38.9)

0.69 (0.26–1.79)

Test for Trend

 

χ2 = 0.50, p = 0.48

Number of mothers and fathers (children)

  

1§

237/608 (39.0)

1.0

≥ 2

67/197 (34.0)

0.82 (0.58–1.16)

Test for Trend

 

χ2 = 1.30, p = 0.25

Age when periods began

  

10–13§

17/39 (43.6)

1.0

14

34/81 (42.0)

0.93 (0.42–2.04)

15

53/166 (31.9)

0.55 (0.27–1.14)

≥ 16

91/227 (40.1)

0.77 (0.38–1.56)

Test for Trend

 

χ2 = 0.46, p = 0.50

Age when periods ended

  

≤ 45§

32/94 (34.0)

1.0

46–49

40/100 (40.0)

1.11(0.60–2.08)

≥ 50

85/198 (42.9)

1.24 (0.69–2.23)

Test for Trend

 

χ2 = 0.74, p = 0.39

Oral contraceptives

  

No§

168/424 (39.6)

1.0

Yes

25/86 (29.1)

0.69 (0.40–1.17)

Test of Homogeneity

 

χ2 = 1.88, p = 0.17

Injectable contraceptives

  

No§

165/425 (38.8)

1.0

Yes

28/87 (32.2)

0.93 (0.55–1.59)

Test of Homogeneity

 

χ2 = 0.07, p = 0.80

  1. * Adjusted for age category < 35, 35–44, 45–54, 55–64, or ≥ 65 sex. ¥ Data were not available for all patients for all variables. § These patients served as the reference group. All values were calculated with the χ2 test with 1 df unless noted otherwise.