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Table 2 Systemic reactions (%) within the first 5 days after vaccination in infants receiving three doses of DTwP//PRP-T, OPV, hepatitis B and the 11PncTD conjugate vaccines

From: Safety and immunogenicity of three doses of an eleven-valent diphtheria toxoid and tetanus protein – conjugated pneumococcal vaccine in Filipino infants

Reaction Dose 1 Dose 2 Dose 3
All systemic 80.4 53.1 46.8
Fever 40.0 22.3 21.3
Vomiting 4.0 2.0 4.3
Diarrhoea 10.0 6.2 10.6
Inconsolable crying 34.0 28.6 14.9
Unusual drowsiness 16.0 2.0 2.1
Irritability 44.0 24.5 10.6
Anorexia 14.0 8.2 6.4
Insomnia 36.0 12.2 10.6
  1. Vaccine administered at 6 (N = 50), 10 (N= 49) and 14 (N= 47) weeks of age