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Table 2 Systemic reactions (%) within the first 5 days after vaccination in infants receiving three doses of DTwP//PRP-T, OPV, hepatitis B and the 11PncTD conjugate vaccines

From: Safety and immunogenicity of three doses of an eleven-valent diphtheria toxoid and tetanus protein – conjugated pneumococcal vaccine in Filipino infants

Reaction

Dose 1

Dose 2

Dose 3

All systemic

80.4

53.1

46.8

Fever

40.0

22.3

21.3

Vomiting

4.0

2.0

4.3

Diarrhoea

10.0

6.2

10.6

Inconsolable crying

34.0

28.6

14.9

Unusual drowsiness

16.0

2.0

2.1

Irritability

44.0

24.5

10.6

Anorexia

14.0

8.2

6.4

Insomnia

36.0

12.2

10.6

  1. Vaccine administered at 6 (N = 50), 10 (N= 49) and 14 (N= 47) weeks of age